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Rhesus negative blood group - 'anti-D' injection

Rhesus negative blood group - 'anti-D' injection

'Anti-D' injection

About 15% of women have a 'Rhesus negative' blood group or 'Rhesus factor' (being 'A negative', 'B negative', 'AB negative' or 'O negative'). If a woman has a negative blood group and she miscarries (or is threatening to miscarry with heavy bleeding during early pregnancy), she may require an injection of 'anti-D immunoglobulin' within 72 hours after the miscarriage (or within 72 hours after the bleeding has commenced for a threatened miscarriage).

Anti-D immunoglobulin is aimed at preventing the woman from developing antibodies in her blood stream (also known as agglutinins'). It is possible for this to happen if a woman with a 'negative' blood group conceives a baby with a 'positive' blood group. The incidence of a woman developing antibodies through miscarriage is thought to be up to 7% if the miscarriage occurs during the first 13 weeks of the pregnancy and up to 20% for miscarriages after 13 weeks.

NOTE:Women with a 'Rhesus positive' blood group ('A positive', 'B positive', 'O positive', 'AB Positive') do not have this health concern because it does not matter what blood group their baby is.

When a woman becomes pregnant, her first pregnancy visit will usually involve some routine blood tests . One of the standard tests performed is called a 'group and antibodies'. This test identifies the woman's:

 
Blood group. Your blood group will be either A, B, O or AB.
'Rhesus factor'. This will be either 'positive' or 'negative'.
Antibodies (also known as 'agglutinins'). If everything is normal, your blood should NOTcontain any antibodies. The result of the antibody test is often written as 'nil detected' or 'negative'.

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